Monofast monofi lament synthetic absorbable surgical suture is indicated for use in general soft tissue approximation and/or ligation, but not for use in cardiovascular tissues and tissues of the central nervous system and also in microsurgery and ophthalmic surgery. The implantation of the MONOFAST monofilament synthetic absorbable surgical suture elicits a minimal infl ammatory reaction which is followed by the development of fi brous connective tissue in place. Progressive loss of tensile strength and eventual absorption of the suture occurs
by means of hydrolysis, where the polymer degrades to adipic acid which is subsequently absorbed and metabolized by the tissues. Absorption begins as a loss of tensile strength without appreciable loss of mass. The retention of the MONOFAST suture is 68-78% of the original tensile strength after the 1st week and approximately 30% after the end of the 2nd week. The absorption of the suture is essentially completed after a period of 90- 110 days. Its original tensile strength is essentially lost 28 days after its implantation.